Lonestar rivals hook up in Houston (You can see the official MLS preview here.) This should be good one to watch. While this game hardly has the status here as the annual Texas-Oklahoma football game (or the Ohio State-Michigan game in my home state), games like this between two teams within a several hours' drive of each other always have a fun intensity to them, due to the mitigation of the home field advantage.
Site search for MLS team shifts to suburbs News on a possible expansion team in Portland
Pro soccer could return to Bay Area in '08 Portland isn't the only city vying for a team; San Jose wants theirs back.
U.S. Soccer hopes to keep rolling OK, so this isn't MLS news, but it relates to the USMNT, so it warrants a link here.